Achievement

  • 2023
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Quantitative risk factor analysis of prior disease condition and socioeconomic status with the multiple myeloma development:nationwide cohort studyScientific Reports-10.1038/s41598-024-52720-1
Risk of Secondary Malignancies After Multiple Myeloma: A Nationwide Case-Control Cohort studyClinical Lymphoma, Myeloma and Leukemia-10.1016/j.clml.2024.05.015
Major cardiovascular events in long-term multiple myeloma survivors: a Korean case-control study (the CAREMM-2105 study)Clinical and Experimental Medicine - 10.1007/s10238-024-01368-2
Dementia incidence in Survivors of Multiple Myeloma: A National Case-Control Study Conducted in Korea(The CAREMM-2106 Study)Clinical Lymphoma, Myeloma and Leukemia-10.1016/j.clml.2024.08.001
Development of a Web Application for Simulating Plasma Drug Concentrations in Patients with Zolpidem IntoxicationPharmaceutics https://doi.org/10.3390/pharmaceutics16050689
Comparison of pharmacodynamics between tegoprazan and dexlansoprazole regarding nocturnal acid breakthrough: a randomized crossover studyGut and Liver https://doi.org/10.5009%2Fgnl220050
A multicenter, retrospective comparison of pregnancy outcomes between groups of preterm labor nulliparous mothers treated with atosiban vs. ritodrine in singleton and multiple pregnanciesTaiwanese Journal of Obstetrics and Gynecology https://doi.org/10.1016/j.tjog.2023.07.009
Establishing Rationale for the Clinical Development of Cell Therapy Products: Consensus between Risk and BenefitInternational Journal of Stem Cells https://doi.org/10.15283/ijsc21189
Pharmacokinetic Interactions Between Bazedoxifene and Cholecalciferol: An Open-Label, Randomized, Crossover Study in Healthy Male VolunteersDrug Design, Development and Therapy https://doi.org/10.2147/DDDT.S399264
Risk of secondary nonhematologic malignancies after allogeneic stem cell transplantation: A nationwide case-control cohort studyInternational Journal of Cancer https://doi.org/10.1002/ijc.34115
Prediction of metabolizing enzyme-mediated clinical drug interactions using in vitro informationTransl Clin Pharmacol https://doi.org/10.12793/tcp.2022.30.e6
DallphinAtoM: Physiologically based pharmacokinetics software predicting human PK parameters based on physicochemical properties, in vitro and animal in vivo dataComputer Methods and Programs in Biomedicine https://doi.org/10.1016/j.cmpb.2022.106662
Metabolic Disease Incidence After Allogeneic Stem Cell Transplantation: A Nationwide Korean Case-Control Study J Clin Endocrinol Metab https://doi.org/10.1210/clinem/dgab900
First-in-human, double-blind, randomized controlled trial of an oral dose of GnRH antagonist, TU2670 in healthy womenJ Clin Endocrinol Metab https://doi.org/10.1210/clinem/dgaa939
Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort studyScientific Reports https://doi.org/10.1038/s41598-020-71208-2
A partial imputation EM-algorithm to adjust the overestimated shape parameter of the Weibull distribution fitted to the clinical time-to-event data Computer Methods and Programs in Biomedicine https://doi.org/10.1016/j.cmpb.2020.105697
First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of a Neuroprotective Poly (ADP-ribose) Polymerase-1 Inhibitor, JPI-289, in Healthy Volunteers Design, Development and Therapy https://doi.org/10.2147/DDDT.S235802
A Population Pharmacokinetic and Pharmacodynamic Model of CKD-519Pharmaceutics - https://doi.org/10.3390/pharmaceutics12060573
Contribution of Trough Concentration Data in the Evaluation of Multiple-Dose Pharmacokinetics for Drugs with Delayed Distributional Equilibrium and Long Half-LifeDrug Design, Development and Therapy - https://doi.org/10.2147/DDDT.S236701
Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA DrugsFrontiers in Pharmacology - https://doi.org/10.3389/fphar.2019.01419
Three-Dimensional Heart Model-Based Screening of Proarrhythmic Potential by In Silico Simulation of Action Potential and ElectrocardiogramsFrontiers in Physiology - https://doi.org/10.3389/fphys.2019.01139
Potency and plasma protein binding of drugs in vitro - a potentially misleading pair for predicting in vivo efficacious concentrations in humansThe Korean Journal of Physiology & Pharmacology - https://doi.org/10.4196/kjpp.2019.23.4.231
Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)Pharmaceutics - https://doi.org/10.3390/pharmaceutics11070336
Application of Pharmacometrics in Pharmacotherapy: Open-Source Software for Vancomycin Therapeutic Drug ManagementPharmaceutics - https://doi.org/10.3390/pharmaceutics11050224
What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision DosingThe AAPS Journal - https://doi.org/10.1208/s12248-018-0286-6
A Randomized, Double-Blind Trial Comparing the Pharmacokinetics of CT-P16, a Candidate Bevacizumab Biosimilar, with its Reference Product in Healthy Adult MalesBioDrugs - https://doi.org/10.1007/s40259-019-00340-x
Physiologically-based pharmacokinetic predictions of intestinal BCRP-mediated drug interactions of rosuvastatin in KoreansThe Korean Journal of Physiology & Pharmacology
Five years of the CiPA project (2013-2018): what did we learn?Translational and Clinical Pharmacology
Population pharmacokinetic analysis of metformin administered as fixed-dose combination in Korean healthy adultsTranslational and Clinical Pharmacology
Development of a user-friendly training software for pharmacokinetic concepts and modelsTranslational and Clinical Pharmacology
Pharmacometrics in Academia: Role for Clinical Researches and Dissemination to Industry in KoreaClinical Therapeutics
Effect of HPV E6/E7 siRNA with Chemotherapeutic Agents on the Regulation of TP53/E2F Dynamic Behavior for Cell Fate DecisionsNeoplasia
Hydrochlorothiazide does not increase furosemide's effects in end-stage renal diseaseTranslational and Clinical Pharmacology
Development and validation of analytical method for the determination of radotinib in human plasma using liquid chromatography-tandem mass spectrometryTranslational and Clinical Pharmacology
Principles of transparency and clinical trial registrationTranslational and Clinical Pharmacology
Tutorial for beginners: the concept of clearance explained using the example of a vacuum cleanerTranslational and Clinical Pharmacology
Drug-drug interaction of microdose and regular-dose omeprazole with a CYp2C19 inhibitor and inducerDrug design, development and therapy
Development of an automated appendix generation system (ARGUS) for clinical study reportsTranslational and Clinical Pharmacology
Decreased potency of fimasartan in liver cirrhosis was quantified using mixed-effects analysisTranslational and Clinical Pharmacology
a 6-month mixed-effect pharmacokinetic model for post-transplant intravenous anti-hepatitis B immunoglobulin prophylaxisDrug Design, Development and Therapy
Human microdosing and mice xenograft data of AGM-130 applied to estimate efficacious doses in patientsCancer chemotherapy and pharmacology
Use of a Target?Mediated Drug Disposition Model to Predict the Human Pharmacokinetics and Target Occupancy of GC 1118, an Anti?epidermal Growth Factor Receptor AntibodyBasic & clinical pharmacology & toxicology
Bortezomib pharmacokinetics in tumor response and peripheral neuropathy in multiple myeloma patients receiving bortezomib-containing therapyAnti-cancer drugs
Volume of distributionTranslational and Clinical Pharmacology
Problems within the post-marketing surveillance system in Korea: Time for a changeTranslational and Clinical Pharmacology
Validation of a liquid chromatography?triple quadrupole mass spectrometric method for the determination of 5?nitro?5′?hydroxy?indirubin?3′?oxime (AGM?130) in human plasma and its application to microdose clinical trialBiomedical Chromatography
R-based reproduction of the estimation process hidden behind NONMEM® Part 2: First-order conditional estimationTranslational and Clinical Pharmacology
Revisiting the well-stirred model of hepatic clearance: QH, CLH and F changing in the same directionTranslational and Clinical Pharmacology
Comparison of oral absorption models for pregabalin: usefulness of transit compartment modelDrug design, development and therapy
Immunogenicity and safety of trivalent split influenza vaccine in healthy Korean adults with low pre-existing antibody levels: an open phase I trialYonsei medical journal
Population pharmacokinetics of imatinib mesylate in healthy Korean subjectsTranslational and Clinical Pharmacology
Tips for the choice of initial estimates in NONMEMTranslational and Clinical Pharmacology
Mixed?effects analysis of increased rosuvastatin absorption by coadministered telmisartanTranslational and Clinical Pharmacology
Population pharmacokinetics and inter-laboratory variability of sildenafil and its metabolite after oral administration in Korean healthy male volunteersTranslational and Clinical Pharmacology
Therapeutic drug monitoring and safety of intravenous voriconazole formulated with sulfobutylether β?cyclodextrin in haematological patients with renal impairmentMycoses
Collaborative Pharmacokinetic?Pharmacodynamic Research for Optimization of Antimicrobial TherapyInfection & chemotherapy
" Physiological spaces and multicompartmental pharmacokinetic models": Fundamentals that pharmacokinetics textbooks do not tell youTranslational and Clinical Pharmacology
Safety of a CRM197-conjugated Haemophilus influenzae type b vaccine in Korean childrenSoutheast Asian J Trop Med Public Health
ClearanceTranslational and Clinical Pharmacology
Statistical basis for pharmacometrics: maximum likelihood estimator and its asymptoticsTranslational and Clinical Pharmacology
R-based reproduction of the estimation process hidden behind NONMEM® Part 1: first-order approximation methodTranslational and Clinical Pharmacology
exposure?response model for sibutramine and placebo: suggestion for application to long-term weight-control drug developmentDrug design, development and therapy
Population pharmacokinetic analysis of the multiple peaks phenomenon in sumatriptanTranslational and Clinical Pharmacology
Clinical pharmacology review for primary health care providers: II. SteroidsTranslational and Clinical Pharmacology
Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndromeJournal of hematology & oncology
Safety and immunogenicity of a single intramuscular dose of a tetanus-diphtheria toxoid (Td) vaccine (BR-TD-1001) in healthy Korean adult subjectsHuman vaccines & immunotherapeutics
Simulation of PET scan timings for receptor occupancy studies of CNS drugs: a simple fixed-time design performed as well as scattered time point designsEuropean journal of clinical pharmacology
Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjectsDrug design, development and therapy
Clinical vaccine developmentClinical and experimental vaccine research
The effects of moxifloxacin on QTc interval in healthy Korean male subjectsDrugs in R&D
Overestimation of Vancomycin Clearance by the Linear Regression Formula in Rodvold's Report: Why?Infection & chemotherapy
From JKSCPT to TCPTranslational and Clinical Pharmacology
Serotonin transporter occupancy of SKL10406 in humans: comparison of pharmacokinetic-pharmacodynamic modeling methods for estimation of occupancy parametersTranslational and Clinical Pharmacology
Clinical Pharmacology Review for Primary Health Care Providers: I. AntihistaminesTranslational and Clinical Pharmacology
Modeling of the parathyroid hormone response after calcium intake in healthy subjectsThe Korean Journal of Physiology & Pharmacology
Early non-steady-state population pharmacokinetics of oral cyclosporine in renal transplant recipientsDrug design, development and therapy
Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: a randomized, open-label, multiple dose, crossover studyBMC Pharmacology and Toxicology
Population pharmacokinetic analysis of piperacillin in burn patientsAntimicrobial agents and chemotherapy
Phase II trial of capecitabine and everolimus (RAD001) combination in refractory gastric cancer patientsInvestigational new drugs
A phase I study of everolimus and CHOP in newly diagnosed peripheral T-cell lymphomasInvestigational new drugs
Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic modelJournal of translational medicine
Pharmacokinetics and Safety of Levodropropizine Controlled Release Tablet after Repeated Dosing in Healthy Male VolunteersJournal of Korean Society for Clinical Pharmacology and Therapeutics
Comparison of the Population Pharmacokinetics and Safety Between Please Orally Soluble Film and VIAGRA® in Healthy Male VolunteersJournal of Korean Society for Clinical Pharmacology and Therapeutics
Pharmacokinetics and Safety of Levodropropizine Controlled Release Tablet after Repeated Dosing in Healthy Male VolunteersJ Korean Soc Clin Pharmacol Ther
Pharmacokinetic?pharmacodynamic model of fimasartan applied to predict the influence of a high fat diet on its blood pressure-lowering effect in healthy subjectsEuropean journal of clinical pharmacology
Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infectionAntimicrobial agents and chemotherapy
Population pharmacokinetic analysis of colistin in burn patientsAntimicrobial agents and chemotherapy
Omeprazole limited sampling strategies to predict area under the concentration?time curve ratios: implications for cytochrome P450 2C19 and 3A phenotypingEuropean journal of clinical pharmacology
Phase 1 trial of S-1 in combination with sorafenib for patients with advanced hepatocellular carcinomaInvestigational new drugs
Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinumBritish journal of cancer
The safety and pharmacokinetics of cyanidin-3-glucoside after 2-week administration of black bean seed coat extract in healthy subjectsThe Korean Journal of Physiology & Pharmacology
Population pharmacokinetic/pharmacodynamic modeling of clopidogrel in Korean healthy volunteers and stroke patientsThe Journal of Clinical Pharmacology
A Review of Fundamentals of Statistical Concepts in Clinical TrialsJournal of Korean Society for Clinical Pharmacology and Therapeutics
Mixed-effect circadian rhythm model for human erythrocyte acetylcholinesterase activity?application to the proof of concept of cholinesterase inhibition by acorn extract in healthy subjects with galantamine as positive controlEuropean journal of clinical pharmacology
Phase I study of intraperitoneal irinotecan in patients with gastric adenocarcinoma with peritoneal seedingCancer chemotherapy and pharmacology
Influence of Simvastatin on Pharmacokinetics/Pharmacodynamics of Aspirin after Oral Co-administration in Healthy VolunteersJournal of Korean Society for Clinical Pharmacology and Therapeutics
Teicoplanin dosing strategy for treatment of Staphylococcus aureus in Korean patients with neutropenic feverYonsei medical journal
Frequently used antiviral agents in the clinical environmentJournal of the Korean Medical Association
Voriconazole-related severe adverse events: clinical application of therapeutic drug monitoring in Korean patientsInternational Journal of Infectious Diseases
Efficacy of vancomycin against Staphylococcus aureus according to inoculum size in a neutropenic mouse infection modelInfection & Chemotherapy
A Population Pharmacokinetic?Pharmacodynamic Model for Simvastatin that Predicts Low?Density Lipoprotein?Cholesterol Reduction in Patients with Primary HyperlipidaemiaBasic & clinical pharmacology & toxicology
Population pharmacokinetics of CPT-11 (irinotecan) in gastric cancer patients with peritoneal seeding after its intraperitoneal administrationEuropean journal of clinical pharmacology
Current state of clinical trials in KoreaJournal of the Korean Medical Association
Population pharmacokinetics of meropenem in burn patientsJournal of antimicrobial chemotherapy
A novel placement method of the Bravo wireless pH monitoring capsule for measuring intragastric pHDigestive diseases and sciences
Comparison of parametric and bootstrap method in bioequivalence testThe Korean Journal of Physiology & Pharmacology
Population pharmacokinetics of intravenous itraconazole in patients with persistent neutropenic feverJournal of clinical pharmacy and therapeutics
Simulation of the AUC changes after generic substitution in patientsJournal of Korean medical science
Population pharmacokinetics of arbekacin in burn patientsEuropean journal of clinical pharmacology
Leveraging prior quantitative knowledge to guide drug development decisions and regulatory science recommendations: impact of FDA pharmacometrics during 2004?2006The Journal of Clinical Pharmacology
Understanding the Drug-Drug InteractionJournal of the Korean Medical Association
Population pharmacokinetics of meropenem in febrile neutropenic patients in KoreaInternational journal of antimicrobial agents
NMDA receptor-dependent inhibition of synaptic transmission by acute ethanol treatment in rat corticostriatal slicesThe Korean Journal of Physiology and Pharmacology